医生路易斯（Dale Midkiff 饰）因工作关系，携妻子瑞秋（Denise Crosby 饰）、女儿艾莉和儿子普吉离开芝加哥搬到了某小镇中，新家近傍公路，屋后有一条蜿蜒小路。邻居杰德（Fred Gwynne 饰）老人介绍小路通往宠物坟场，那里埋着多年来死在公路上的动物们。第一天上班，路易斯就遭遇了一位重伤死亡的患者，他仿佛看到死者对他说话，对方声称为了感谢他的救助，将阻止他接近鬼魂。不久，儿女的猫被车撞死，杰德带领路易斯将猫埋葬在山上的印第安坟场，而猫竟然复活了，担心女儿伤心的路易斯松了一口气，但复活的猫咪变得异常暴力与恶臭。数天后，小儿子不幸被车撞死，伤心欲绝的路易斯想把儿子的尸体埋入印第安坟场……

杰克凯斯（尼克·诺特 Nick Nolte 饰）是一名长期在警界未能有所突破的资深警探。他一直感到郁闷和失意，经常酗酒来逃避现实。与此同时，在黑人区长大的雷吉汉蒙德（艾迪·墨菲 Eddie Murphy 饰）一直是一个惯犯，从年轻时就开始犯罪活动。然而，无论杰克还是雷吉，他们都渴望能够改变自己的生活状况，追求新的机会和改正错误。 　　故事的转折点发生在瓦尔登旅馆之中，重刑犯艾伯特（詹姆斯·瑞马尔 James Remar 饰）和他的搭档比利（索尼·兰哈姆 Sonny Landham 饰）越狱成功，并躲藏在这家旅馆中。他们用假名字掩盖身份，并计划继续他们的犯罪行动。与此同时，杰克和他的同事文森特和阿尔根被派去调查一宗案件，却不幸成为艾伯特的目标。杰克决定为同事报仇，他请求上司允许他独立办案。

The film tells the story of single mother “Kara” (Elizabeth Roberts) who moves from New York to the quiet countryside with her two children for a job opportunity she can’t afford to turn down. The family moves into their humble new guesthouse. Kara begins her work as a private nurse to “Walter,” (Bruce Davison) a man stricken with multiple sclerosis and an appraiser of rare antiquities with a secretive past. 　　Her teenage son, Jesse, (Arman Darbo) is unhappy about this most of all. Losing his friends and moving to the middle of nowhere hasn’t made his job of looking after his little sister, “Cambria,” (Chloe Perrin) any easier. 　　Doom precedes them. “Akiba,” (Treva Etienne) a shady international associate of Walter’s, brings with him a mysterious relic of ancient origin. “Kara” encounters run in with a local sheriff played by genre veteran actor Denise Crosby. 　　All too quickly they discover the relic contains more than just legends. Inside, waits a terrifying creature born of ancient darkness and pure instinct…a pre-historic cave Spider unlike the modern world has ever seen.